Health Canada reports that world-wide until 1999 there were recorded over 5,000 cases of accidental laboratory infections and 190 deaths. At higher biosafety levels, precautions may include airflow systems, multiple containment rooms, sealed containers, positive pressure personnel suits, established protocols for all procedures, extensive personnel training, and high levels of security to control access to the facility. Īt the lowest level of biosafety, precautions may consist of regular hand-washing and minimal protective equipment. Facilities with these designations are also sometimes given as P1 through P4 (for pathogen or protection level), as in the term P3 laboratory. In Canada the four levels are known as Containment Levels. In the European Union, the same biosafety levels are defined in a directive. In the United States, the Centers for Disease Control and Prevention (CDC) have specified these levels. The levels of containment range from the lowest biosafety level 1 (BSL-1) to the highest at level 4 (BSL-4). Essential features of a biosafety level 4 (BSL-4) laboratory Ī biosafety level ( BSL), or pathogen/protection level, is a set of biocontainment precautions required to isolate dangerous biological agents in an enclosed laboratory facility.
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